ef hand motifs การใช้

The protein parvalbumin has EF hand motifs used for calcium binding.
Notably, the protein contains three EF hand motifs that function as binding sites for Ca 2 + ions.
PLC-?1 also possesses a classical leucine-rich nuclear export signal ( NES ) in its EF hand motif, as well as a Nuclear localization signal within its linker region.
It has three EF hand motifs and is structurally related to calmodulin and troponin C . Parvalbumin is localised in fast-contracting muscles, where its levels are highest, as well as in the brain and some endocrine tissues.
The Ca 2 +-binding site is a novel EF hand motif on the essential light chain and is stabilized by linkages involving the heavy chain and both light chains, accounting for the requirement of all three chains for Ca 2 + binding and regulation in the intact myosin molecule.